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Landmark Trial Will Evaluate the Impact of Treating Anemia on Cardiovascular Outcomes Landmark Trial Will Evaluate the Impact of Treating Anemia on Cardiovascular Outcomes



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Old 04-22-2005, 12:47 AM
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Landmark Trial Will Evaluate the Impact of Treating Anemia on Cardiovascular Outcomes
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Landmark Trial Will Evaluate the Impact of Treating Anemia on Cardiovascular Outcomes in Patients with Chronic Kidney Disease and Type 2 Diabetes

3/28/05

TREAT Study Highlighted in March American Heart Journal

THOUSAND OAKS, Calif., Mar 28, 2005 (BUSINESS WIRE)

Amgen Inc. (Nasdaq:AMGN), the world's largest biotechnology company, today announced that TREAT (Trial to Reduce Cardiovascular Events with Aranesp(R) Therapy), an Amgen-sponsored trial, is featured in the March 2005 issue of the American Heart Journal. TREAT is the first randomized controlled trial specifically designed to determine whether treating anemia reduces cardiovascular events in individuals with chronic kidney disease (CKD) and Type 2 diabetes.

"Existing data suggest that anemia increases the risk of cardiovascular events in patients with chronic kidney disease and Type 2 diabetes," said TREAT lead investigator, Marc Pfeffer, M.D., Ph.D., Interim Chief of Medicine at Brigham and Women's Hospital and Professor at Harvard Medical School. "The inclusion of the TREAT rationale and methodology in the American Heart Journal highlights the cardiology community's recognition of the need to further understand and study the link between chronic kidney disease, diabetes, anemia and cardiovascular disease."

According to the American Heart Association, people with CKD, even those in the early stages of the disorder, are in the highest-risk group for cardiovascular disease. Recent data show that the majority of CKD patients die before they ever reach dialysis. The increased cardiovascular risk found in patients with CKD is attributable to several risk factors, including anemia. Anemia is a common complication of CKD that worsens as kidney function declines.

The American Heart Journal article reviews the role of diabetes and anemia in cardiovascular disease . . . http://www.stockhouse.com/news/news.asp?tick=AMGN&newsid=2700468
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