Clinical review -Autologous transfusion.
Elizabeth S Vanderlinde, chief resident a, Joanna M Heal, associate clinical professor of medicine c, Neil Blumberg, director, transfusion medicine and blood bank b.
a Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Box 608, 601 Elmwood Avenue, Rochester, NY 14642, USA, b Transfusion Medicine Unit, University of Rochester Medical Center, c Department of Medicine, University of Rochester Medical Center
Correspondence to: N Blumberg Neil_Blumberg@urmc.rochester.edu
Since the AIDS epidemic of the early 1980s the interest in alternatives to allogeneic transfusion has grown, particularly
for elective surgery. One alternative that currently accounts
for over 5% of the blood donated in the United States and some
countries in Europe is autologous transfusion, obtained primarily
by preoperative donation. Although autologous transfusion is used
less widely in the United Kingdom than in the United States, guidelines
on its use have recently been published in the United Kingdom.
1 We describe the three main types of autologous transfusion and
draw attention to the advantages and disadvantages of each technique
(see table A on bmj.com). We also review the evidence from observational
and controlled trials comparing autologous with allogeneic transfusion.
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