Aprotinin; friend or foe? A review of recent medical literature.

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Aprotinin; friend or foe? A review of recent medical literature.

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12-19-2006, 08:46 PM

Sharon Grant Sharon Grant is offline

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Aprotinin; friend or foe? A review of recent medical literature.

Eur J Anaesthesiol. 2007 Jan;24(1):6-14. Epub 2006 Nov 14

Aprotinin; friend or foe? A review of recent medical literature.

Royal Brompton and Harefield NHS Trust, Harefield Hospital, Department of Cardiothoracic Anaesthesiaand Critical Care, Harefield, UK.

SummaryRecent articles published in peer review journals have questioned the safety of using aprotinin in patients having heart surgery. Also, evidence has been published to suggest an increase in renal events in patients given aprotinin when compared to those where tranexamic acid was used. The present review will focus principally on the first of these articles in relation to previously published data and experience.

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