04-15-2005, 03:33 PM
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Transfusion-related acute lung injury following allogeneic bone marrow transplantatio
Source:
Intern Med. 2004 Nov;43(11):1068-72
Full Text Article:
http://tinyurl.com/cspn8
Transfusion-related acute lung injury following allogeneic bone marrow transplantation in a patient with acute lymphoblastic leukemia.
Noji H, Shichishima T, Ogawa K, Shikama Y, Ohto H, Maruyama Y.
First Department of Internal Medicine, Fukushima Medical University, Fukushima.
Transfusion-related acute lung injury (TRALI) is a clinical syndrome characterized by bilateral pulmonary edema in association with transfusions. We encountered a 23-year-old woman with acute lymphoblastic leukemia, in whom TRALI without anti-human leukocyte antigen class I and anti-granulocyte antibodies developed following allogeneic bone marrow transplantation. TRALI improved mainly in association with treatment of saline and ventilation support after several days, but graft-versus-host disease and thrombotic microangiopathy developed, resulting in death due to multiple organ failure. This case indicates that TRALI can also occur following allogeneic bone marrow transplantation.
Publication Types: PMID: 15609705 [PubMed - indexed for MEDLINE]
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