Eur J Cardiothorac Surg 2004;25:468-470
© 2004 Elsevier Science NL
Case report
Successful CABG in a patient with paroxysmal nocturnal hemoglobinuria
Yuji Naito*, Masato Nakajima, Hidenori Inoue, Koji Tsuchiya
Department of Cardiovascular Surgery, Yamanashi Central Hospital, 1-1-1, Fujimi, Kofu-shi, Yamanashi 400-0027, Japan
Received 11 June 2003; received in revised form 4 October 2003; accepted 24 November 2003.
* Corresponding author. Tel.: +81-55-253-7111; fax: +81-55-253-8011
e-mail:
ujinaito@aol.com
Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon acquired disorder of blood cells characterized by intravascular hemolysis due to an inordinate sensitivity to complement-mediated membrane damage. This report documents coronary artery revascularization in a patient with PNH, which has not been described in the literature so far. We used the on-pump procedure in the present patient and successfully performed revascularization by taking prophylactic measures against hemolysis.
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