Blood Fractions Guide - Background
This is a discussion on Blood Fractions Guide - Background within the Glossary of Terms forum; Blood Fractions Guide - Background BACKGROUND. In the early days of blood transfusion, all transfusions ...
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06-11-2005, 07:09 PM
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Blood Fractions Guide - Background
BACKGROUND. In the early days of blood transfusion, all transfusions were of whole blood. Fresh whole blood was given to patients who had either lost a significant quantity of their own blood or who had become anemic for one reason or another. Thus, those early transfusions of blood were primarily given to replace lost volume, or to restore the patient's hemoglobin level to normal values and thereby correct tissue hypoxia. It was also felt that the presence of platelets and clotting factors in the transfused blood would help to arrest any bleeding. With the advent of blood banking however, medical science realized that by separating certain components from blood and only administering the ones specifically needed, the donated blood would go further and wastage could be reduced. From then on, when a patient was anemic or it was felt that the oxygen-carrying capacity of his blood needed enhancing, he would only be given red blood cells. A patient suffering hypovolemia or shock might be given plasma to restore normal blood volume, or for its albumin content, or because the clotting factors could address a bleeding disorder. Platelets might be administered to a patient with ongoing bleeding, and white blood cells might be given to a patient whose immune system was struggling to combat an infection. Red cells, white cells and platelets are often given to patients whose bone marrow function has become impaired due to chronic illness, or as a result of chemo- or radiotherapy. The red cells, white cells and platelets are referred to by hematologists as the formed elements. Because the formed elements and the plasma are the major constituents of blood, were the first components to be separated from whole blood, and because they play such a fundamental role in the immediate life support and maintenance of the body, many have termed them the "primary components" of blood. The process of separating blood into its various medically useful components is known as pheresis. In the course of time the four primary components were further processed so as to yield a number of other products, sometimes referred to as "minor blood fractions" ... Full article can be found on the NoBlood Wiki http://wiki.noblood.org/FractionsBackground Last edited by Informaticus; 08-31-2008 at 12:05 AM. Reason: To direct readers to the NoBlood Wiki     
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| The Following 4 Users Say Thank You to Editors For This Useful Post: | ||
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06-15-2005, 01:51 PM
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In some religions the four primary components of blood would be unacceptable. The minor blood fractions can be conscientiously accepted by some. Thank you for discussing an interesting subject.
Milton
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06-15-2005, 05:22 PM
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Excellent Information. I would like to use the graph in upcoming presentations. Many viewing this information may wish to know that Hemoglobin makes up 33% of the red blood cell. Since most who accept fractions and reject whole blood, tend to accept minor fractions, They may baulk at a product that is 1/3 of a primary component and takes on the primary function of the blood cell.
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06-16-2005, 06:56 AM
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I recently attended the NATA conference in Prague,and there we were informed that in Russia, there has been a significant advancement in another version of EPO, is there any news on this product.?
David Asher
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06-16-2005, 12:37 PM
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While I am not clear regarding exactly the type of detailed information you are looking for, I entered Polyheme in the 'Search' at the top of the page and NoBlood.org came back with 31 hits. At some point, 'details' regarding Polyheme will come together in connection with our Fractions Guide Project.
Hope this helps.
__________________
Larry Eitel President & Webmaster Click here and see who are advancing transfusion alternatives and blood management. Can you spare a cup of coffee? Click here. Thank you. 
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06-22-2005, 05:32 AM
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A beautiful and practical explanation
Thanks for this simple, practical and beautiful way of explain the point of the components of blood.I´m thinking to apply your model in classroom. Do you know a model (algorithm) to explain the use of alternatives in trauma settings? Thank again.
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Dr. José R. Luciano S.
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06-24-2005, 07:17 AM
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Appropriate Blood Use - Algorithm for Trauma Setting
Development of an algorithm would be a good exercise for our members.
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Mr. Jan B. Wade Blood Management Consultant Enhance Outcomes - Control Cost For Information Call - 360 296-1807 
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06-27-2005, 06:17 AM
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Larry, What an excellent resource for patients! And so clear to understand. My thanks to you. Pam Pennigar, NP, Duke University.
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