noblood - Prothrombin Complex Concentrates

Prothrombin Complex Concentrates are a sterile, freeze-dried powder containing purified human clotting factors II, IX and X. It is prepared from collected from voluntary donors.

Primary component of origin

Plasma.

Percent of component

Production

The product is prepared from plasma. The solution is sterilised, freeze-dried and heated in the dry state to reduce the potential for viral transmission. Other ingredients are human plasma proteins 400 mg (which includes low levels of factors V and VII). May be suspended in a solution of plasma.

Medicinal Value

Used in the treatment of bleeding in patients with deficiency of factors IX, II or X and in patients with acquired prothrombin complex factor deficiency requiring partial or complete reversal (e.g. reversal of warfarin anti-coagulant therapy). [1]