Clotting Factors

Blood clotting factors are plasmaproteins that normally work with platelets to help the blood clot. Clotting factors may be produced from plasma products or manufactured artificially using a special technological procedure; manufactured proteins are called recombinant factor concentrates. Without clotting factors, bleeding would not stop after an injury. Individual concentrated blood clotting factors can be given to people who have an inherited bleeding disorder, such as hemophilia or von Willebrand's disease, and to those who are unable to produce enough clotting factors (usually because of severe infection or liver disease).

The 13 primary clotting factors are listed here:

Factor Name

1. Fibrinogen
2. Prothrombin
3. Tissue Factor (TF)
4. Calcium
5. Proaccelerin
6. Accelerin
7. Proconvertin
8. Antihemophiliac A
9. Antihemophiliac B (Christmas Factor)
10. Stuart-Prower Factor
11. Plasma thromboplastin antecedent (PTA)
12. Hageman Factor
13. Fibrin stabilizing factor (FSF)

Primary component of origin

Platelets.

Percent of component

Production

Medicinal Value

Risks

Pharmaceuticals, found in

Alternatives

Factoids

See also

Types of Transfusions