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The combination contains many but not all of the components of FFP. The ability of any product or component to restore normal coagulation is dependent on the underlying deficiency. I am not sure of the circumstances that led the intensivists to believe FFP was indicated, so there is no way to tell whether the combination would have been just as efficacious as FFP. PROTHROMBINEX contains concentrated factor IX, factor II, factor X and low level of factor VII. Cryopreciptate contains Factors VIII, vWF, fibrinogen, XIII, and fibronectin. FFP contains the majority of all known factors, but essentially no cells or platelets. In addition to the coagulation factors, FFP also contains approximately 500 mg of fibrinogen. The fibrinogen in 1 unit of FFP is approximately equal to the amount of fibrinogen found in 2 units of cryoprecipitate.