Transfusion Trigger <7
This is a discussion on Transfusion Trigger <7 within the Ask a Professional forum; As coordinators what do you do to assist your medical staff in limiting the use ...
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07-08-2008, 06:30 PM
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Transfusion Trigger <7
As coordinators what do you do to assist your medical staff in limiting the use of allogeneic blood transfusions when your trigger is set to <7 ? Do most of your transfusions events take place between 7 - 8 ? What do you do if a good percentage are between 8-9?
Any thoughts would be appreciated.      
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07-09-2008, 09:20 AM
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See this new article
Impact of red blood cell transfusion on clinical o...[Am J Cardiol. 2008] - PubMed Result
Stratified analyses showed a protective effect of transfusion in patients with nadir hemoglobin </=8 g/dL (adjusted HR 0.13, 95% CI 0.03 to 0.65, p = 0.013). By contrast, transfusion was associated with increased mortality in patients with nadir hemoglobin >8 g/dL (adjusted HR 2.2, 95% CI 1.5 to 3.3; p <0.0001). Richard it is always been a hazy crystal ball when the native Hgb level falls below 8 esp for patients with CAD. Below this point the literature has shown increased morbidity and mortality in patients with CAD. Transfusing allogeneic RBCs in general, but above this optimal native Hgb level, has also shown to increase morbidity and mortality and in the vast majority of cases are unnecessary. State of the Art Management in Cardiac Surgery (courtesy of Global Blood Resources)
__________________
Keith A. Samolyk CCP, LCP Global Blood Resources LLC P.O. Box 383 Somers CT. 06071 Tel (800) - 942 - 9243 Fax (860) - 285 - 0289 www.mybloodfirst.com
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