We are encountering problems here in the Philippines with regards to Dengue outbreaks.
I would appreciate any information that could be shared in managing Dengue Hemmorhagic Fever without resorting to the use of Platelet concentrate or Fresh Frozen Plasma. These are being recommended by the doctors when they encounter a rapid decrease in the platelet count.
Thank you so much.

Yours truly,
alrimorin

Aminocaproic acid is recommended to control bleeding associated with reduced platelet counts. (Archives of Internal Medicene, Sept. 1989,pp 1959-61,Vol.149, No. 9 ) Page 1961: " In this study, responses to aminocaproic acid therapy were clinically dramatic. Once therapy with aminocaproic acid was initiated, platelet transfusions were no longer necessary in the majority of our patients."
Recombinant activated factor V11 has also been used to control bleeding in patients with Dengue Shock Syndrome. For further info. please contact Dept. of Pediatrics,Faculty of Medicine, Ramathibodi Hospital, Mahidol University,Bangkok, Thailand. raajs@mahidol.ac.th