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Risk versus Benefit
Here is a post that lists three of the current platelet stimulating drugs. http://www.noblood.org/medical-artic...6987#post16987
All have side effects ranging from mild to severe. The decision to use one of these medications must be based on a risk versus benefit analysis.
To illustrate: A lady is walking through the jungle when her path is cut by a very deep ravine. Ahead of her she sees a bridge made of vines and wooden planks. The vines look fairly rotten and some of the planks are missing. She decides the risk of using the bridge is too great. Suddenly a wild boar appears and charges her. She runs across the bridge.
In a life threatening situation one might decide to use a drug with fairly severe side effects. It is a matter of risk versus benefit or in some cases it is risk versus death.