Most fractions that come from the pharmacy are heat treated or washed with detergent. Therefore, HIV would not be a concern as truly outside the body, it is a weak virus. However, a few years back some of Factor VIII was removed from the market do to fear of Cruetzfeld Jacob or mad cow disease. There was some reported cases of that transmission with Human Growth Hormone. Since we really don't know the mode of transmission, or what can destroy it, it remains a matter of concern. However, that is a concern with even the meat you eat. A good book to read is "Deadly Feasts". Biological fractions, such as Cryo, is different. They carry the same risk as any blood product. Hope this helps. yvette

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