Which products mimic any one of the four primary components of blood?

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Old 08-01-2004, 07:40 PM
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Which products mimic any one of the four primary components of blood?



I understand that many products contain very small derivatives of a primary component, i.e., proteins, hormones, etc. I am interested in learning more about products that are essentially primary components that have been slightly altered or modified and function like the primary component.
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Old 08-01-2004, 07:46 PM
prosen
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Hemoglobin-based oxygen carriers (HBOCs) fall into this category since they substantially consist of red blood cells.
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Old 08-02-2004, 08:39 AM
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Red Cells

Larry states - "contain very small derivatives of a primary component"


According to the site Health/How Stuff Works - http://health.howstuffworks.com/blood3.htm Red Cells are 33 percent hemoglobin - Hemoglobin Based Oxygen Carriers mimic a main function of red blood cells i.e. picking up oxygen from the lungs and delivering a percentage of that oxygen to the tissues.

I am attaching a small PowerPoint showing RBC and Plasma percentage of total blood.
Attached Files
File Type: ppt Percentages Large and Small.ppt (31.0 KB, 335 views)
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Old 08-02-2004, 09:31 AM
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Jan - great teaching tool. Thanks for sharing.
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Old 08-02-2004, 10:10 AM
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Does anyone know the names of some of the HBOC products mentioned?
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Old 08-02-2004, 10:49 AM
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PolyHeme is an HBOC currently being tested in clinical trials across the U.S.. It was developed by Northfield Labs. Hemopure is also a HBOC. It was developed by Biopure Corporation.
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Old 08-02-2004, 11:15 AM
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Slightly off topic though a related question...

When a product such as PolyHeme is being tested in clinical trials, are patients given an option to choose whether or not to accept the use of the product?


Quote:
Originally Posted by LWilson
PolyHeme is an HBOC currently being tested in clinical trials across the U.S.. It was developed by Northfield Labs. Hemopure is also a HBOC. It was developed by Biopure Corporation.
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Old 08-02-2004, 11:16 AM
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The HLC in Chicago is attending an inservice at Loyola Medical Center on PolyHeme on Wednesday this week. They are using it without requiring consent in the ambulance and in the ED. Therefore, it becomes a problem for those who refuse it for whatever reason. I hope to have some in-depth information as of Wednesday and will report on it then.
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Old 08-02-2004, 11:29 AM
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We were told that those that don't want it might have to wear some kind of identification to indicate they don't want it. However all that is on the agenda for the meeting on Wednesday here in Chicago.
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Old 08-02-2004, 11:39 AM
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Jan, would you please contact someone on your local HLC ( :-) ) and ask them to request PolyHeme's scheduled inservices around the country? This is obviously an issue that would be of great interest to the Witness community. You guys must have a GREAT HLC Chairman!
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blood fractions, components, cryoprecipitate, products, trauma


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