I would also like to thank you for this concise explanation. We had to do a lot of research last Sept for a 77-yr old mother-in-law who was involved in a collision and sustained fractures in two vertebrae and broken ribs and collapsed lung and hematoma on the brain. One thing we were asked as a family is if she would take the cryoprecipitate. I called the local blood bank and they informed me as to how it was extracted and ended up being only 1/500th of whole blood. It had to be reconstituted before administration and they usually use plasma, but they could also do it with saline, I believe, or some similar substance that would ease the conscience of those who won't take plasma.
Kathy